Endocrine Abstracts

Introduction: Blood transfusion is critical for survival in Thalassemia major. Hypertransfusion therapy increased the frequency of complications due to iron overload. The aim of this study was evaluation of endocrine disturbances in patients with thalassemia major older than 10 years old.Materials and methods: Fifty six patients with thalassemia major greater than 10 years enrolled. Patients have been examined to determine their pubertal status and stand...

Hyperemesis gravidarum is characterized by prolonged, severe nausea and vomiting in early pregnancy that. It occurs in about 1.5% of pregnancies and is more common in Asian women than in white women. Many patients do not need anti thyroid drugs, except in patients with severe nausea and vomiting and thyroid dysfunction after 18–20 weeks of pregnancy.Material and methods: One hundred and thirty-five patients with hyperemesis gravidarum whom admitted ...

Introduction: Metformin is the only biguanide that is currently in use as an oral hypoglycemic agent in type 2 diabetes mellitus (DM). There are reports about the vitamin B12 deficiency in metformin users. This study was aimed to evaluate the vitamin B12 deficiency in patients with type 2 DM using metformin or other hypoglycemic agents.Methods: A descriptive-comparative study was performed on 400 patients with type 2 DM presenting t...

Objectives: The present study aimed to investigate the prevalence of thyroid dysfunction in the elderly women of Tabriz city, the largest city in North West Iran.Design: Cross-sectional study.Setting and participants: By using the records of the local household registry, a sample of 1150 subjects was drawn by simple random sampling. After the exclusion of nonresponse subjects, 1000 subjects aged between 60 and 89 years (mean 64.5&#...

Introduction: Osteoporotic hip fracture is one of the serious complications of bone loss. These fractures constitute almost 20% of orthopedics wards admissions. Due to lack of precise statistical data of osteoporotic hip fracture rates in IRAN, and absence of previous investigations regarding the problem in Tabriz (a large city in north west of IRAN), we planed a study to survey frequency of this epidemic in over 50 years old residents of Tabriz.Material...

Introduction: Urtica diocia extract has been used for treatment of diabetes mellitus for many centuries. Hypoglycemic effects of U. diocia have been shown in multiple studies. The present study was designed to determinate the possible mechanisms of hypoglycemic effects of U. diocia on human muscle cells.Methods and materials: In cell culture laboratory of Drug Applied Research Center of Tabriz University (Medical Sciences) in IRAN hu...

Introduction: Urtica diocia extract has been used for treatment of diabetes mellitus for many centuries. Hypoglycemic effects of U. diocia have been shown in multiple studies. The present study was designed to determinutese the possible mechanisms of hypoglycemic effects of U. diocia on RIN5F Rat Pancreatic β cells.Methods and materials: In cell culture laboratory of Drug Applied Research Center of Tabriz University (Medical Sci...